R-449A
Also known as: R449A, Opteon XP40, Genetron 449A
EPA SNAP-approved R-404A and R-507A replacement from Chemours. GWP 1,397. Non-flammable A1. Similar performance to R-448A with slightly different composition.
Regulatory Timeline
Chemours (then DuPont) develops Opteon XP40 (R-449A) as R-404A replacement
EPA SNAP listing for R-449A in commercial refrigeration applications
What R-449A Is
R-449A (Opteon XP40) is a four-component HFO/HFC blend of R-32, R-125, R-1234yf, and R-134a, developed by Chemours as a lower-GWP commercial refrigeration alternative to R-404A. Its GWP of 1,397 is nearly identical to R-448A (1,387) and represents the same approximate 65% reduction from R-404A.
R-449A carries A1 safety classification, making it a non-flammable drop-in retrofit candidate for R-404A systems using the standard retrofit process. It is widely distributed through refrigerant wholesalers and is the Chemours-branded alternative where R-448A is the Honeywell offering.
The two products perform similarly in commercial refrigeration applications. Preference between R-448A and R-449A often comes down to regional supplier availability, manufacturer endorsement, and existing contractor supply chain relationships.
Frequently Asked Questions
Refrigerants R-449A Commonly Replaces
Dominant in supermarket and commercial refrigeration. With GWP of 3,922 — the highest of any common refrigerant — it faces accelerated phasedown pressure under AIM Act.
Azeotropic HFC blend for low-temperature commercial refrigeration. GWP of 3,985 is the highest of any common refrigerant — subject to accelerated phasedown pressure.
HFO/HFC blend for transport and commercial refrigeration. GWP 2,140 — 45% lower than R-404A. A1 safety class. Partially transitional; R-448A and R-449A offer better GWP reduction.